Disadvantaged backgrounds can leave a lifelong accelerated aging marker in children

Children from economically disadvantaged backgrounds may experience a biological imprint that could impact their health and longevity, according to a recent study conducted by researchers at Imperial College London. The study, which involved over 1,000 European children, found that socioeconomic status can influence the aging trajectory of children, with those from less privileged backgrounds showing shorter telomeres—a biomarker for aging.

Telomeres are protective caps at the end of chromosomes that shorten with age, making them a measurable marker of biological aging. The research, published in eBioMedicine, is the largest of its kind to examine the impact of economic status on children’s aging trajectories.

The study revealed that children from higher affluence backgrounds had longer telomeres compared to those from lower affluence backgrounds. Girls also showed longer telomeres than boys, while children with higher body mass index had shorter telomeres. The researchers also found that children from more affluent households had lower levels of the stress hormone cortisol.

Dr. Oliver Robinson, one of the senior authors of the study, emphasized the importance of addressing these disparities early in a child’s life to prevent long-term health consequences. He noted that children from low affluence backgrounds may experience additional biological wear and tear equivalent to approximately 10 years of aging at a cellular level compared to their more affluent peers.

The study population included children from the HELIX exposome cohort, which included participants from various European countries. The findings underscore the need for public health policies to reduce health inequalities and provide all children with a fair start in life.

While the study had some limitations, such as capturing relative rather than absolute telomere length and a limited range of economic backgrounds, it sheds light on the impact of socioeconomic status on children’s health and underscores the importance of addressing these disparities early on. By understanding and addressing these issues, we can work towards ensuring a healthier future for all children, regardless of their economic background.