Certain type of hormone therapy increases breast cancer risk, study finds

Hormone therapy has long been a popular treatment for menopausal symptoms in women. However, a new study published in The Lancet Oncology suggests that certain types of hormone therapy may increase the risk of breast cancer in women under the age of 55.

The study specifically looked at the use of estrogen plus progestin, a synthetic form of progesterone, in women with a uterus. It found that this combination therapy increased the risk of breast cancer in this group of women. On the other hand, estrogen alone was found to reduce the risk of breast cancer. This distinction is important because women with a uterus need to take both estrogen and progestin to prevent thickening of the uterine lining, which can lead to endometrial cancer.

Dr. Céline Gounder, a medical contributor for CBS News, explained that the study participants were divided into two groups based on whether they had a uterus or not. For women without a uterus, estrogen alone was deemed safe and effective in reducing menopausal symptoms without increasing the risk of breast cancer.

The findings of this study are significant as they challenge previous research from the Women’s Health Initiative, which raised safety concerns about hormone therapy. The newer research focuses on women who start hormone therapy around the age of menopause, providing more accurate and relevant data for healthcare professionals to consider.

It’s important to note that hormone replacement therapy, like any medication, comes with risks. According to the Mayo Clinic, hormone therapy can increase the risk of heart disease, stroke, blood clots, and certain cancers. However, it can also reduce the risk of cancer, prevent bone loss, and alleviate menopausal symptoms.

Ultimately, the timing and type of hormone therapy are crucial factors to consider when weighing the benefits and risks. Consulting with a healthcare provider and taking into account family history and individual factors is essential in determining the most appropriate treatment option.

In conclusion, hormone replacement therapy remains an effective treatment for menopausal symptoms, but it’s important to approach it with caution and awareness of potential risks. By staying informed and working closely with healthcare professionals, women can make informed decisions about their health and well-being during menopause.