Digital health outreach can improve lung cancer screening

The latest study published in JAMA, co-led by researchers at the UNC Lineberger Comprehensive Cancer Center and Wake Forest University School of Medicine, has revealed promising results in increasing lung cancer screening for high-risk individuals through a direct-to-patient digital health program.

Despite being the leading cause of cancer-related deaths in the United States, only a small percentage of eligible individuals undergo recommended lung cancer screening. Early detection through screening can significantly reduce the risk of lung cancer death, as highlighted by the National Cancer Institute.

The study identified various barriers to screening, including difficulties in identifying eligible patients, lack of awareness about screening recommendations among patients and providers, and limited time for counseling and shared decision-making during regular primary care visits.

To address these challenges, researchers implemented the mPATH-Lung online program in a randomized clinical trial involving 1,333 screening-eligible individuals with a history of smoking. Participants using the digital program showed a 25% completion rate for screening CT scans at 16 weeks, compared to 17% in the control group. Importantly, screening rates improved across all demographic and socioeconomic groups, with no reported complications from screening-related procedures.

Lead researcher Dr. Daniel S. Reuland emphasized the scalability and effectiveness of digital outreach in enhancing lung cancer screening. The mPATH-Lung program provided eligible patients with educational resources, decision aids, and the option to schedule a screening program appointment, resulting in significant improvements in screening rates.

Co-author Dr. Alison Brenner highlighted the impact of digital outreach in addressing disparities in access to screening, particularly among underserved populations. The study demonstrated the potential of digital health programs to complement traditional care provided during primary care visits.

The research team expressed pride in translating their findings into real-world solutions for patients in North Carolina and beyond. The study’s publication in JAMA underscores the significance of digital health initiatives in improving lung cancer screening rates and ultimately saving lives.

For more information, the study citation can be found in JAMA under the title “A Direct-to-Patient Digital Health Program for Lung Cancer Screening.” The DOI is 10.1001/jama.2025.17281, and the full article can be accessed on the JAMA website.

This groundbreaking research was conducted by the University of North Carolina at Chapel Hill School of Medicine, showcasing their commitment to advancing healthcare through innovative digital solutions. Visit their website for further information on their research initiatives and contributions to the medical field.