Jamie-Lynn Sigler Kept Her MS Diagnosis a Secret for 25 Years
Jamie-Lynn Sigler recently opened up in an emotional interview with ABC about her guest appearance on “Grey’s Anatomy” as a doctor with multiple sclerosis. The role hit close to home for Sigler, who was diagnosed with MS 25 years ago and felt compelled to keep it a secret out of fear of losing work opportunities.
Reflecting on her journey, Sigler shared, “To think back 25 years ago — when I was diagnosed and having to keep it a secret, thinking that if anybody knew that I had MS, that meant that I would never work again — and to now be in a position where my having MS inspired a role in a storyline on a show like ‘Grey’s Anatomy,’ I never would have believed you.”
At the time of her diagnosis, Sigler was just 20 years old and working on the iconic HBO series “The Sopranos.” It wasn’t until 2017 that she decided to go public with her MS diagnosis, sitting down with the National Multiple Sclerosis Society to share her story.
On January 15, viewers saw Sigler make her debut on “Grey’s Anatomy” as Dr. Laura Kaplan, a urologist with MS. In her episode, she imparts valuable advice to Dr. Richard Webber (played by James Pickens Jr.) on the best approach to treating his prostate cancer.
For Sigler, the role was an opportunity to showcase someone living with MS in a position of strength and authority. She aimed to provide an authentic portrayal of a person thriving despite the challenges of the condition.
Describing the emotional impact of her performance, Sigler revealed, “My very first take, where I do say the words that ‘I have MS,’ was very emotional for me.” The experience of bringing her personal journey to life on screen was a powerful moment for the actress.
By bravely sharing her story and bringing visibility to MS through her role on “Grey’s Anatomy,” Jamie-Lynn Sigler continues to inspire others and advocate for greater understanding and representation of individuals living with the condition.


